David Searls and the Linguistics of DNA

David Searls is probably the first to use sophisticated linguistic methods in the analysis and classification of features in DNA sequences. He also originally suggested the idea that grammars could be used to describe the structure of non-macromolecules, presenting a very early version of what later became our terminal form. Our debt to him is significant.

A pleasant introduction to the application of linguistics to DNA sequence analysis can be found in Searls, D. B., 1992. The linguistics of DNA. Am. Scient. 80: 579-591. The origin of the idea of compound grammars is in Searls, D. B. A prospectus for a molecular logic. UniSys internal report, Paoli PA (undated).



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